The report of Fexofenadina of excess amount be fixed to be, therefore, the effect which is defined is not healthy. N. death 110 time for the human of the mouse and 5000 mg/kg highest dose adults who are nominated is happened to the test. As for research above that the rut/rat which dies being the same centralization which 400 times is a match to the dose where the human of the adult is nominated is not shown. Research of the human the false medicine is compared two degrees reaches from the single dose of the everyday dose of 800 magnesium of 690 magnesium of the month when it does not have important adverse effect clinically. In order to create the piperidine of the part, two phenyl groups are brought using the reaction of Grignard of the foreign country for the tertiary alcohol, first. As for the group then it is protected to be the aldehyde of amine alchilati, then aldehyde is recovered from acid and deprotection. The remaining part of the molecule is created by time due to the alkylation of iodomethane which happens from carbanion of nitrile. The group of nitrile adding water is disassembled in carboxyl group acid. (After workup) the bromide is aryl lithiated in order to create the blend of organolithium which can connect with the aldehyde part in order to give fexofenadine.
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